Serum alpha-actinin antibody status in systemic lupus erythematosus and its potential in the diagnosis of lupus nephritis

• Main Authors: Mansour Babaei (Author), Zahra Rezaieyazdi (Author), Nayereh Saadati (Author), Massoud Saghafi (Author), Maryam Sahebari (Author), Bahram Naghibzadeh (Author), Habibollah Esmaily (Author)
• Format: Book
• Published: Babol University of Medical Sciences, 2016-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: In lupus nephritis (LN), deposition of pathogenic autoantibodies in the glomeruli is mediated via cross-reactivity with alpha-actinin. Association of serum alpha-actinin antibody (AαA) with LN has been shown in a few studies but the results are controversial. Methods: Eighty pa...