Amitriptyline-Based Biodegradable PEG-PLGA Self-Assembled Nanoparticles Accelerate Cutaneous Wound Healing in Diabetic Rats

Amitriptyline-Based Biodegradable PEG-PLGA Self-Assembled Nanoparticles Accelerate Cutaneous Wound Healing in Diabetic Rats

The aim of this work was to study the healing activity of amitriptyline (Amitrip) in rat diabetic wounds. A nanoformula of the drug was prepared as Amitrip-based biodegradable PEG-PLGA self-assembled nanoparticles (Amitrip-NPs) with a mean particle size of 67.4 nm. An in vivo investigation was condu...

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Main Authors: Hani Z. Asfour (Author), Nabil A. Alhakamy (Author), Osama A. A. Ahmed (Author), Usama A. Fahmy (Author), Mohamed A. El-moselhy (Author), Waleed Y. Rizg (Author), Adel F. Alghaith (Author), Basma G. Eid (Author), Ashraf B. Abdel-Naim (Author)
Format: Book
Published: MDPI AG, 2022-08-01T00:00:00Z.
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