Rho/ROCK Inhibition Promotes TGF-β3-Induced Tenogenic Differentiation in Mesenchymal Stromal Cells

• Autores principales: Michaela Melzer (Autor), Susanna Schubert (Autor), Simon Franz Müller (Autor), Joachim Geyer (Autor), Alina Hagen (Autor), Sabine Niebert (Autor), Janina Burk (Autor)
• Formato: Libro
• Publicado: Hindawi Limited, 2021-01-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

Mesenchymal stromal cells (MSC) represent a promising therapeutic tool for tendon regeneration. Their tenogenic differentiation is crucial for tissue engineering approaches and may support their beneficial effects after cell transplantation in vivo. The transforming growth factor (TGF)-β, signalling...