Identification of key pharmacological components and targets for Aidi injection in the treatment of pancreatic cancer by UPLC-MS, network pharmacology, and in vivo experiments

• Main Authors: Haojia Wang (Author), Zhishan Wu (Author), Xiaotian Fan (Author), Chao Wu (Author), Shan Lu (Author), Libo Geng (Author), Antony Stalin (Author), Yingli Zhu (Author), Fanqin Zhang (Author), Jiaqi Huang (Author), Pengyun Liu (Author), Huiying Li (Author), Leiming You (Author), Jiarui Wu (Author)
• Format: Book
• Published: BMC, 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Pancreatic cancer is one of the most lethal cancers worldwide. Aidi injection (ADI) is a representative antitumor medication based on Chinese herbal injection, but its antitumor mechanisms are still poorly understood. Materials and methods In this work, the subcutaneous xenograft...