Approaches to handling missing or "problematic" pharmacology data: Pharmacokinetics

• Main Authors: Donald J. Irby (Author), Mustafa E. Ibrahim (Author), Anees M. Dauki (Author), Mohamed A. Badawi (Author), Sílvia M. Illamola (Author), Mingqing Chen (Author), Yuhuan Wang (Author), Xiaoxi Liu (Author), Mitch A. Phelps (Author), Diane R. Mould (Author)
• Format: Book
• Published: Wiley, 2021-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Missing or erroneous information is a common problem in the analysis of pharmacokinetic (PK) data. This may present as missing or inaccurate dose level or dose time, drug concentrations below the analytical limit of quantification, missing sample times, or missing or incorrect covariate inf...