The protein family TcTASV-C is a novel Trypanosoma cruzi virulence factor secreted in extracellular vesicles by trypomastigotes and highly expressed in bloodstream forms.

• Main Authors: Lucas D Caeiro (Author), Catalina D Alba-Soto (Author), Mariana Rizzi (Author), María Elisa Solana (Author), Giselle Rodriguez (Author), Agustina M Chidichimo (Author), Matías E Rodriguez (Author), Daniel O Sánchez (Author), Gabriela V Levy (Author), Valeria Tekiel (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2018-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

TcTASV-C is a protein family of about 15 members that is expressed only in the trypomastigote stage of Trypanosoma cruzi. We have previously shown that TcTASV-C is located at the parasite surface and secreted to the medium. Here we report that the expression of different TcTASV-C genes occurs simult...