A novel nitroreductase-enhanced MRI contrast agent and its potential application in bacterial imaging

Nitroreductases (NTRs) are known to be able to metabolize nitro-substituted compounds in the presence of reduced nicotinamide adenine dinucleotide (NADH) as an electron donor. NTRs are present in a wide range of bacterial genera and, to a lesser extent, in eukaryotes hypoxic tumour cells and tumorou...

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Main Authors: Yun Liu (Author), Leilei Zhang (Author), Marc Nazare (Author), Qingqiang Yao (Author), Hai-Yu Hu (Author)
Format: Book
Published: Elsevier, 2018-05-01T00:00:00Z.
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