Modeling Mycobacterium tuberculosis early granuloma formation in experimental human lung tissue

• Main Authors: Venkata Ramanarao Parasa (Author), Muhammad Jubayer Rahman (Author), Anh Thu Ngyuen Hoang (Author), Mattias Svensson (Author), Susanna Brighenti (Author), Maria Lerm (Author)
• Format: Book
• Published: The Company of Biologists, 2014-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The widely used animal models for tuberculosis (TB) display fundamental differences from human TB. Therefore, a validated model that recapitulates human lung TB is attractive for TB research. Here, we describe a unique method for establishment of TB infection in an experimental human lung tissue mod...