Successful Low-Cost Scaffold-Free Cartilage Tissue Engineering Using Human Cartilage Progenitor Cell Spheroids Formed by Micromolded Nonadhesive Hydrogel

• Main Authors: Mellannie P. Stuart (Author), Renata A. M. Matsui (Author), Matheus F. S. Santos (Author), Isis Côrtes (Author), Mayra S. Azevedo (Author), Karina R. Silva (Author), Anderson Beatrici (Author), Paulo Emílio C. Leite (Author), Priscila Falagan-Lotsch (Author), José M. Granjeiro (Author), Vladimir Mironov (Author), Leandra S. Baptista (Author)
• Format: Book
• Published: Hindawi Limited, 2017-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The scaffold-free tissue engineering using spheroids is pointed out as an approach for optimizing the delivery system of cartilage construct. In this study, we aimed to evaluate the micromolded nonadhesive hydrogel (MicroTissues®) for spheroid compaction (2-day culture) and spontaneous chondrogenesi...