Involvement of CXCL12/CXCR4 in the motility of human first-trimester endometrial epithelial cells through an autocrine mechanism by activating PI3K/AKT signaling

• मुख्य लेखकों: Jiayi Zheng (लेखक), Danni Qu (लेखक), Chen Wang (लेखक), Ling Ding (लेखक), Wenhui Zhou (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: BMC, 2020-02-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Abstract Background CXCL12(chemokine ligand 12, CXCL12) and its receptors CXCR4 are widely expressed in maternal-fetal interface and plays an adjust role in materno-fetal dialogue and immune tolerance during early pregnancy. This study aimed to evaluate the role and mechanism of self-derived CXCL12...