Nonfunctional overreaching and hepatic adaptations of APPL1 and APPL2

• Main Authors: Gustavo P. Morais (Author), Larissa Gaioto de Vicente (Author), Luciana da C. Oliveira (Author), Ana P. Pinto (Author), Alisson L. da Rocha (Author), Bruno C. Pereira (Author), José R. Pauli (Author), Adelino S. R. da Silva (Author)
• Format: Book
• Published: Universidade Estadual Paulista (UNESP), 2017-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract AIMS Previously, we verified that overtrained mice upregulated the TRB3 levels, its association with Akt, and the hepatic concentrations of glycogen. It is known that APPL1 can limit the interaction between TRB3 and Akt, playing an important role in the glucose homeostasis. Thus, we verifie...