Pristimerin inhibits thioredoxin reductase in the treatment of non-small cell lung cancer

• Главные авторы: Yajun Chu (Автор), Qianhe Xu (Автор), Xiedong Zhou (Автор), Qiuying Nie (Автор), Xiaojun Yao (Автор), Jianguo Fang (Автор), Junmin Zhang (Автор)
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• Опубликовано: Compuscript Ltd, 2024-06-01T00:00:00Z.
• Предметы: article
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Elevated cellular oxidative stress is a common marker of cancer cell dysregulation caused by malignant transformation. Thioredoxin reductase (TrxR, encoded by TXNRD) is a crucial enzyme that regulates cellular oxidative stress and the survival of many types of cancer cells. Therefore, targeting TrxR...