Estimation of Body Fat Percentage for Clinical Pharmacokinetic Studies in Children

• Main Authors: Thomas P. Green (Author), Helen J. Binns (Author), Huali Wu (Author), Adolfo J. Ariza (Author), Eliana M. Perrin (Author), Maheen Quadri (Author), Christoph P. Hornik (Author), Michael Cohen‐Wolkowiez (Author)
• Format: Book
• Published: Wiley, 2021-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Obesity is a prevalent childhood condition and the degree of adiposity appears likely to be an important covariate in the pharmacokinetics (PKs) of many drugs. We undertook these studies to facilitate the evaluation and, where appropriate, quantification of the covariate effect of body fat percentag...