In Silico Approach: Effect of the Oxidation Iron State (Heme-Group) in Steroidogenesis Pathways

• Main Authors: David Mora-Martinez (Author), Jorge Organista-Nava (Author), Jesús Sandoval-Ramirez (Author), Berenice Illades-Aguiar (Author), Alan Carrasco-Carballo (Author)
• Format: Book
• Published: Institute for Researches and Community Services Universitas Muhammadiyah Palangkaraya, 2022-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

One of the main design features of enzyme regulators for the CYPs is the presence of a heme-group and different oxidation states in iron atoms. The selective inhibition of a CYP-enzyme can help to reduce the formation of steroidal molecules that causes undesirable disorders and is, therefore a topic...