Randomized Control Trial of Postnatal rhIGF-1/rhIGFBP-3 Replacement in Preterm Infants: Post-hoc Analysis of Its Effect on Brain Injury

• Main Authors: Sandra Horsch (Author), Alessandro Parodi (Author), Boubou Hallberg (Author), Mariya Malova (Author), Isabella M. Björkman-Burtscher (Author), Ingrid Hansen-Pupp (Author), Neil Marlow (Author), Kathryn Beardsall (Author), David Dunger (Author), Mirjam van Weissenbruch (Author), Lois E. H. Smith (Author), Mohamed Hamdani (Author), Alexandra Mangili (Author), Norman Barton (Author), Luca A. Ramenghi (Author), Ann Hellström (Author), David Ley (Author), ROPP- 2008-01 Study Team (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Postnatal insulin-like growth factor-1 (IGF-1) replacement with recombinant human (rh)IGF-1 and IGF binding protein-3 (rhIGF-1/rhIGFBP-3) is being studied as a potential treatment to reduce comorbidities of prematurity. We have recently reported on a phase II, multicenter, randomized, co...