Adult Langerhans cell histiocytosis presenting as metachronous colonic polyps

• Main Authors: Aloísio Felipe-Silva (Author), Maurício Saab Assef (Author), Rodrigo Azevedo Rodrigues (Author), Carla Pagliari (Author)
• Format: Book
• Published: University of São Paulo, 2013-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Langerhans cell histiocytosis (LCH) is a rare disease characterized by proliferation of Langerhans-type cells that express CD1a, Langerin (CD207) and S100 protein. Birbeck granules are a hallmark by ultrastructural examination. LCH presents with a wide clinical spectrum, ranging from solitary lesion...