Connective tissue disease-related interstitial lung disease is alleviated by tripterine through inhibition of the PI3K/Akt, apoptosis, and TNF-α signalling pathways

• Main Authors: Wen Zhu (Author), Yifan Wang (Author), Chenxi Liu (Author), Yunxia Wu (Author), Yehui Li (Author), Yue Wang (Author)
• Format: Bog
• Udgivet: Frontiers Media S.A., 2022-11-01T00:00:00Z.
• Fag: article
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Background: Interstitial lung disease (ILD) is the major cause of morbidity and mortality in patients with various rheumatic diseases. However, more interventions need to be sought. Tripterine, an extract of Tripterygium wilfordii Hook. F, has been widely studied for its powerful anti-inflammatory e...