Ablation of USP21 in skeletal muscle promotes oxidative fibre phenotype, inhibiting obesity and type 2 diabetes

• Main Authors: Ayoung Kim (Author), Ja Hyun Koo (Author), Xing Jin (Author), Wondong Kim (Author), Shi‐Young Park (Author), Sunghyouk Park (Author), Eugene P. Rhee (Author), Cheol Soo Choi (Author), Sang Geon Kim (Author)
• Format: Book
• Published: Wiley, 2021-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Skeletal muscle as a metabolic consumer determines systemic energy homeostasis by regulating myofibre type conversion and muscle mass control. Perturbation of the skeletal muscle metabolism elevates the risk of a variety of diseases including metabolic disorders. However, the reg...