A novel antibody surrogate biomarker to monitor parasite persistence in Trypanosoma cruzi-infected patients.

• Main Authors: Maan Zrein (Author), Elodie Granjon (Author), Lucie Gueyffier (Author), Julie Caillaudeau (Author), Peter Liehl (Author), Hans Pottel (Author), Clareci Silva Cardoso (Author), Claudia Di Lorenzo Oliveira (Author), Lea Campos de Oliveira (Author), Tzong-Hae Lee (Author), Ariela Mota Ferreira (Author), Antonio Luiz P Ribeiro (Author), Michael P Busch (Author), Ester Cerdeira Sabino (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2018-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND:Trypanosoma cruzi parasite, the causative agent of Chagas disease, infects about six million individuals in more than 20 countries. Monitoring parasite persistence in infected individuals is of utmost importance to develop and evaluate treatments to control the disease. Routine screening...