The Effects of PPAR Stimulation on Cardiac Metabolic Pathways in Barth Syndrome Mice

• Main Authors: Caitlin Schafer (Author), Vicky Moore (Author), Nupur Dasgupta (Author), Sabzali Javadov (Author), Jeanne F. James (Author), Alexander I. Glukhov (Author), Arnold W. Strauss (Author), Zaza Khuchua (Author)
• Format: Book
• Published: Frontiers Media S.A., 2018-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Aim: Tafazzin knockdown (TazKD) in mice is widely used to create an experimental model of Barth syndrome (BTHS) that exhibits dilated cardiomyopathy and impaired exercise capacity. Peroxisome proliferator-activated receptors (PPARs) are a group of nuclear receptor proteins that play essential roles...