Melatonin Attenuates Sepsis-Induced Acute Lung Injury Through Improvement of Epithelial Sodium Channel-Mediated Alveolar Fluid Clearance Via Activation of SIRT1/SGK1/Nedd4-2 Signaling Pathway

Acute lung injury is characterized by alveolar vascular barrier injury, and protein-rich pulmonary oedema. Alveolar fluid clearance is closely related to the prognosis of patients with acute lung injury. Melatonin has been shown to have a protective effect on multiple organ injury induced by sepsis....

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Main Authors: Jing Li (Author), Longfei Liu (Author), Xiaojun Zhou (Author), Xianzhou Lu (Author), Xianrong Liu (Author), Guojuan Li (Author), Jianwu Long (Author)
Format: Book
Published: Frontiers Media S.A., 2020-12-01T00:00:00Z.
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