Age-dependent pattern of cerebellar susceptibility to bilirubin neurotoxicity in vivo in mice

• Main Authors: Giulia Bortolussi (Author), Gabriele Baj (Author), Simone Vodret (Author), Giulia Viviani (Author), Tamara Bittolo (Author), Andrés F. Muro (Author)
• Format: Book
• Published: The Company of Biologists, 2014-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Neonatal jaundice is caused by high levels of unconjugated bilirubin. It is usually a temporary condition caused by delayed induction of UGT1A1, which conjugates bilirubin in the liver. To reduce bilirubin levels, affected babies are exposed to phototherapy (PT), which converts toxic bilirubin into...