Docking studies on novel analogs of quinolones against DNA gyrase of Escherichia coli

• Auteurs principaux: Cristian Davila (Auteur), Lorena Llach (Auteur), Guillermo Salgado-Moran (Auteur), Rodrigo Ramirez-Tagle (Auteur)
• Format: Livre
• Publié: GarVal Editorial Ltda., 2018-09-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Context: Bacterial resistance to antibiotics is the inevitable consequence of the use of antimicrobial agents. Thus, quinolones are an important class of antibacterials; these agents generally consist of a 1-subtituted-1,4-dihydro-4-oxopyridine-3-carboxylic acid moiety combined with an aromatic or h...