The BACH1/Nrf2 Axis in Brain in Down Syndrome and Transition to Alzheimer Disease-Like Neuropathology and Dementia

Down syndrome (DS) is the most common genetic cause of intellectual disability that is associated with an increased risk to develop early-onset Alzheimer-like dementia (AD). The brain neuropathological features include alteration of redox homeostasis, mitochondrial deficits, inflammation, accumulati...

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Main Authors: Marzia Perluigi (Author), Antonella Tramutola (Author), Sara Pagnotta (Author), Eugenio Barone (Author), D. Allan Butterfield (Author)
Format: Book
Published: MDPI AG, 2020-08-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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