A phase II dose evaluation pilot feasibility randomized controlled trial of cholecalciferol in critically ill children with vitamin D deficiency (VITdAL-PICU study)

• Main Authors: Katie O'Hearn (Author), Kusum Menon (Author), Hope A. Weiler (Author), Karin Amrein (Author), Dean Fergusson (Author), Anna Gunz (Author), Raul Bustos (Author), Roberto Campos (Author), Valentina Catalan (Author), Siegfried Roedl (Author), Anne Tsampalieros (Author), Nick Barrowman (Author), Pavel Geier (Author), Matthew Henderson (Author), Ali Khamessan (Author), Margaret L. Lawson (Author), Lauralyn McIntyre (Author), Stephanie Redpath (Author), Glenville Jones (Author), Martin Kaufmann (Author), Dayre McNally (Author), the Canadian Critical Care Trials Group (Author)
• Format: Book
• Published: BMC, 2023-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Vitamin D deficiency (VDD) is highly prevalent in the pediatric intensive care unit (ICU) and associated with worse clinical course. Trials in adult ICU demonstrate rapid restoration of vitamin D status using an enteral loading dose is safe and may improve outcomes. There have be...