Mechanisms Underlying Dopaminergic Regulation of Nicotine-Induced Kinetic Tremor

• المؤلفون الرئيسيون: Masaki Kato (مؤلف), Naofumi Kunisawa (مؤلف), Saki Shimizu (مؤلف), Higor A. Iha (مؤلف), Yukihiro Ohno (مؤلف)
• التنسيق: كتاب
• منشور في: Frontiers Media S.A., 2022-06-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

Nicotine induces kinetic tremor, which resembles pharmacological features of essential tremors, via activating the inferior olive (IO) neurons. Since nicotine is known to enhance dopamine release by stimulating α4β2 and/or α6 nACh receptors, we examined the effects of various dopamine receptor ligan...