Progression-specific genes identified in microdissected formalin-fixed and paraffin-embedded tissue containing matched ductal carcinoma in situ and invasive ductal breast cancers

• Main Authors: Silke Schultz (Author), Harald Bartsch (Author), Karl Sotlar (Author), Karina Petat-Dutter (Author), Michael Bonin (Author), Steffen Kahlert (Author), Nadia Harbeck (Author), Ulrich Vogel (Author), Harald Seeger (Author), Tanja Fehm (Author), Hans J. Neubauer (Author)
• Format: Book
• Published: BMC, 2018-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background The transition from ductal carcinoma in situ (DCIS) to invasive breast carcinoma (IBC) is an important step during breast carcinogenesis. Understanding its molecular changes may help to identify high-risk DCIS that progress to IBC. Here, we describe a transcriptomic profiling ana...