Functional and molecular characterisation of EO771.LMB tumours, a new C57BL/6-mouse-derived model of spontaneously metastatic mammary cancer

• Main Authors: Cameron N. Johnstone (Author), Yvonne E. Smith (Author), Yuan Cao (Author), Allan D. Burrows (Author), Ryan S. N. Cross (Author), Xiawei Ling (Author), Richard P. Redvers (Author), Judy P. Doherty (Author), Bedrich L. Eckhardt (Author), Anthony L. Natoli (Author), Christina M. Restall (Author), Erin Lucas (Author), Helen B. Pearson (Author), Siddhartha Deb (Author), Kara L. Britt (Author), Alexandra Rizzitelli (Author), Jason Li (Author), Judith H. Harmey (Author), Normand Pouliot (Author), Robin L. Anderson (Author)
• Format: Book
• Published: The Company of Biologists, 2015-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The translation of basic research into improved therapies for breast cancer patients requires relevant preclinical models that incorporate spontaneous metastasis. We have completed a functional and molecular characterisation of a new isogenic C57BL/6 mouse model of breast cancer metastasis, comparin...