Inhibitory effects of sulfenimides on human and bovine carbonic anhydrase enzymes

• Main Authors: Hasan Yakan (Author), Gürkan Bilir (Author), Şükriye Çakmak (Author), Ömer Taş (Author), Nalan Türköz Karakullukçu (Author), Ercan Soydan (Author), Halil Kütük (Author), Coşkun Güçlü (Author), Murat Şentürk (Author), Tayfun Arslan (Author), Seyhan Öztürk (Author), Ercüment Aksakal (Author), Deniz Ekinci (Author)
• Format: Book
• Published: Taylor & Francis Group, 2023-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A series of sulfenimide derivatives (1a-i) were investigated as inhibitors of human (hCA-I, hCA-II) and bovine (bCA) carbonic anhydrase enzymes. The compounds were synthesised by the reaction of substituted thiophenols with phthalimide by means of an effective, simple and eco-friendly method and the...