Case report: NUDT15 polymorphism and severe azathioprine-induced myelosuppression in a young Chinese female with systematic lupus erythematosus: a case analysis and literature review

Azathioprine is clinically used as an immunosuppressant for treating autoimmune diseases. However it has narrow therapeutic indices due to frequent myelosuppression. Polymorphic variants of genes coding for thiopurine S-methyltransferase (TPMT) and nucleoside diphosphate-linked moiety X motif 15 (NU...

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Main Authors: Juan Gu (Author), Yupei Lin (Author), Yuhe Wang (Author)
Format: Book
Published: Frontiers Media S.A., 2023-05-01T00:00:00Z.
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3rd Floor Main Library

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