Genome scale analysis of pathogenic variants targetable for single base editing
Abstract Background Single nucleotide variants account for approximately 90% of all known pathogenic variants responsible for human diseases. Recently discovered CRISPR/Cas9 base editors can correct individual nucleotides without cutting DNA and inducing double-stranded breaks. We aimed to find all...
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| Main Authors: | , , |
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| Format: | Book |
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BMC,
2020-09-01T00:00:00Z.
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| Call Number: |
A1234.567 |
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| Copy 1 | Available |