Dual Responsive poly(vinyl caprolactam)-Based Nanogels for Tunable Intracellular Doxorubicin Delivery in Cancer Cells

• Päätekijät: Kummara Madhusudana Rao (Tekijä), Maduru Suneetha (Tekijä), Dachuru Vinay Kumar (Tekijä), Hyeon Jin Kim (Tekijä), Yong Joo Seok (Tekijä), Sung Soo Han (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: MDPI AG, 2022-04-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

In this work, doxorubicin (Dox)-encapsulated poly(vinyl caprolactam) (PVCL)-based three-dimensional nanogel networks were developed and were crosslinked with disulfide linkages. The nanogels degrade rapidly to low molecular weight chains in the presence of the typical intracellular concentration of...