The Protection of Midazolam Against Immune Mediated Liver Injury Induced by Lipopolysaccharide and Galactosamine in Mice

• Main Authors: Jian Li (Author), Hong Tan (Author), Xiaona Zhou (Author), Chunpan Zhang (Author), Hua Jin (Author), Yue Tian (Author), Xinyan Zhao (Author), Xinmin Li (Author), Xuelian Sun (Author), Meili Duan (Author), Dong Zhang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2019-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objectives: Liver macrophages agitated by Lipopolysaccharide (LPS) can enhance immuno-inflammatory responses in the liver which mediate liver injury and result in dysfunction. Midazolam has been reported to have inhibitory effects on activated immunity and escalated inflammation, however, what the e...