Mechanisms of exercise-induced muscle damage and fatigue: Intracellular calcium accumulation

• Main Authors: Yutaka Kano (Author), Takashi Sonobe (Author), Tadakatsu Inagaki (Author), Mizuki Sudo (Author), David C Poole (Author)
• Format: Book
• Published: Japanese Society of Physical Fitness and Sports Medicine, 2012-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Contraction-induced compromise of muscle function and, in the extreme, muscle damage has been linked to loss of Ca2+ homeostasis and resultant sustained elevation of intracellular Ca2+ ([Ca2+]i). Against a background of in vitro approaches, a novel in vivo model permits investigation of the impact o...