Design, in silico and pharmacological evaluation of a peptide inhibitor of BACE-1

Introduction: Alzheimer's disease (AD) is the main type of dementia, caused by the accumulation of amyloid plaques, formed by amyloid peptides after being processed from amyloid precursor protein (APP) by γ- and ß-secretases (BACE-1). Although amyloid peptides have been well established for AD,...

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Main Authors: Renata Boldin (Author), Bianca Cestari Zychar (Author), Luis Roberto C. Gonçalves (Author), Juliana Mozer Sciani (Author)
Format: Book
Published: Frontiers Media S.A., 2023-06-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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