Oxygenator Is the Main Responsible for Leukocyte Activation in Experimental Model of Extracorporeal Circulation: A Cautionary Tale

• Main Authors: Alessio Rungatscher (Author), Maddalena Tessari (Author), Chiara Stranieri (Author), Erika Solani (Author), Daniele Linardi (Author), Elisabetta Milani (Author), Alessio Montresor (Author), Flavia Merigo (Author), Beatrice Salvetti (Author), Tiziano Menon (Author), Giuseppe Faggian (Author)
• Format: Book
• Published: Hindawi Limited, 2015-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In order to assess mechanisms underlying inflammatory activation during extracorporeal circulation (ECC), several small animal models of ECC have been proposed recently. The majority of them are based on home-made, nonstandardized, and hardly reproducible oxygenators. The present study has generated...