Effects of 17-AAG on the RIP1/RIP3/MLKL pathway during the development of heart failure following myocardial infarction in rats

Effects of 17-AAG on the RIP1/RIP3/MLKL pathway during the development of heart failure following myocardial infarction in rats

In a previous study, we suggested that the Hsp90 inhibitor 17-AAG prevents cardiac dysfunction in the failing heart following myocardial infarction in rats. Although it is assumed that the RIP1/RIP3/MLKL necroptotic pathway, which comprises client proteins for Hsp90, is involved; however, the relati...

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Main Authors: Tetsuro Marunouchi (Author), Takumi Ito (Author), Sumika Onda (Author), Lina Kyo (Author), Kirara Takahashi (Author), Manami Uchida (Author), Emi Yano (Author), Kouichi Tanonaka (Author)
Format: Book
Published: Elsevier, 2021-10-01T00:00:00Z.
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