The protocol for the Cannabidiol in children with refractory epileptic encephalopathy (CARE-E) study: a phase 1 dosage escalation study

• Main Authors: Darren Reithmeier (Author), Richard Tang-Wai (Author), Blair Seifert (Author), Andrew W. Lyon (Author), Jane Alcorn (Author), Bryan Acton (Author), Scott Corley (Author), Erin Prosser-Loose (Author), Darrell D. Mousseau (Author), Hyun J. Lim (Author), Jose Tellez-Zenteno (Author), Linda Huh (Author), Edward Leung (Author), Lionel Carmant (Author), Richard J. Huntsman (Author)
• Format: Book
• Published: BMC, 2018-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Initial studies suggest pharmaceutical grade cannabidiol (CBD) can reduce the frequency of convulsive seizures and lead to improvements in quality of life in children affected by epileptic encephalopathies. With limited access to pharmaceutical CBD, Cannabis extracts in oil are b...