Exosomal miR-335 derived from mature dendritic cells enhanced mesenchymal stem cell-mediated bone regeneration of bone defects in athymic rats

• Main Authors: Zhongliu Cao (Author), Yanfeng Wu (Author), Lingling Yu (Author), Lingfeng Zou (Author), Liu Yang (Author), Sijian Lin (Author), Jue Wang (Author), Zhen Yuan (Author), Jianghua Dai (Author)
• Format: Book
• Published: BMC, 2021-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Transplantation of bone marrow-derived mesenchymal stem cells (BM-MSCs) embedded in a bio-compatible matrix has been demonstrated as a promising strategy for the treatment of bone defects. This study was designed to explore the effect and mechanism of exosomes derived from mature...