Integration of metabolomics and transcriptomics reveals the therapeutic mechanism underlying Chelidonium majus L. in the treatment of allergic asthma

• Main Authors: Renguang Wang (Author), Xintong Sui (Author), Xin Dong (Author), Liming Hu (Author), Zhimeng Li (Author), Hang Yu (Author), Cuicui Li (Author), Guoxin Ji (Author), Shumin Wang (Author)
• Format: Book
• Published: BMC, 2024-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Chelidonium majus is a well-known traditional Chinese medicine, and has been reported of the effect in relieving cough and asthma. However, the mechanism of action is still unknown. Methods Asthmatic SD rats were first sensitized and established through ovalbumin (OVA) motivation...