Zoledronic acid prevents pagetic-like lesions and accelerated bone loss in the p62P394L mouse model of Paget's disease

Paget's disease of bone (PDB) is an age-related metabolic bone disorder, characterised by focally increased and disorganised bone remodelling initiated by abnormal and hyperactive osteoclasts. The germline P392L mutation of SQSTM1 (encoding p62) is a strong genetic risk factor for PDB in humans...

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主要な著者: Anna Daroszewska (著者), Lorraine Rose (著者), Nadine Sarsam (著者), Gemma Charlesworth (著者), Amanda Prior (著者), Kenneth Rose (著者), Stuart H. Ralston (著者), Robert J. van 't Hof (著者)
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出版事項: The Company of Biologists, 2018-09-01T00:00:00Z.
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