Potential Role of the Mitochondria for the Dermatological Treatment of Papillon-Lefèvre

• Үндсэн зохиолчид: Beatriz Castejón-Vega (Зохиогч), Maurizio Battino (Зохиогч), José L. Quiles (Зохиогч), Beatriz Bullon (Зохиогч), Mario D. Cordero (Зохиогч), Pedro Bullón (Зохиогч)
• Формат: Ном
• Хэвлэсэн: MDPI AG, 2021-01-01T00:00:00Z.
• Нөхцлүүд: article
• Онлайн хандалт: Connect to this object online.

The Papillon-Lefèvre syndrome (PLS) is a rare autosomal recessive disorder caused by mutations in the Cathepsin C (CTSC) gene, characterized by periodontitis and palmoplantar hyperkeratosis. The main inflammatory deficiencies include oxidative stress and autophagic dysfunction. Mitochondria are the...