Potential Role of the Mitochondria for the Dermatological Treatment of Papillon-Lefèvre

Potential Role of the Mitochondria for the Dermatological Treatment of Papillon-Lefèvre

The Papillon-Lefèvre syndrome (PLS) is a rare autosomal recessive disorder caused by mutations in the Cathepsin C (CTSC) gene, characterized by periodontitis and palmoplantar hyperkeratosis. The main inflammatory deficiencies include oxidative stress and autophagic dysfunction. Mitochondria are the...

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Main Authors: Beatriz Castejón-Vega (Author), Maurizio Battino (Author), José L. Quiles (Author), Beatriz Bullon (Author), Mario D. Cordero (Author), Pedro Bullón (Author)
Format: Book
Published: MDPI AG, 2021-01-01T00:00:00Z.
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