Potential Role of the Mitochondria for the Dermatological Treatment of Papillon-Lefèvre

• 主要な著者: Beatriz Castejón-Vega (著者), Maurizio Battino (著者), José L. Quiles (著者), Beatriz Bullon (著者), Mario D. Cordero (著者), Pedro Bullón (著者)
• フォーマット: 図書
• 出版事項: MDPI AG, 2021-01-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

The Papillon-Lefèvre syndrome (PLS) is a rare autosomal recessive disorder caused by mutations in the Cathepsin C (CTSC) gene, characterized by periodontitis and palmoplantar hyperkeratosis. The main inflammatory deficiencies include oxidative stress and autophagic dysfunction. Mitochondria are the...