Applied Concepts in PBPK Modeling: How to Extend an Open Systems Pharmacology Model to the Special Population of Pregnant Women

• Main Authors: André Dallmann (Author), Juri Solodenko (Author), Ibrahim Ince (Author), Thomas Eissing (Author)
• 格式: 圖書
• 出版: Wiley, 2018-07-01T00:00:00Z.
• 主題: article
• 在線閱讀: Connect to this object online.

This tutorial presents the workflow of adapting an adult physiologically based pharmacokinetic (PBPK) model to the pregnant populations using the Open Systems Pharmacology (OSP) software suite (www.open-systems-pharmacology.org). This workflow is illustrated using a previously published PBPK model f...