A population pharmacokinetic and pharmacokinetic‐pharmacodynamic analysis of vupanorsen from phase I and phase II studies
Abstract Vupanorsen (PF‐07285557) is a second‐generation ligand‐conjugated 2'O‐methoxyethyl modified antisense oligonucleotide designed to target angiopoietin‐like 3 (ANGPTL3) mRNA expressed by the liver, shown to reduce lipids and apolipoproteins in subjects with dyslipidemia. Using pooled dat...
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| Main Authors: | , , |
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| Format: | Book |
| Published: |
Wiley,
2023-07-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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| Call Number: |
A1234.567 |
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| Copy 1 | Available |