Temporary CXCR3 and CCR5 Antagonism Following Vaccination Enhances Memory CD8 T Cell Immune Responses

• Main Authors: Rui Li (Author), Nan Zhang (Author), Miaomiao Tian (Author), Zihan Ran (Author), Mingjun Zhu (Author), Haiyan Zhu (Author), Fangting Han (Author), Juan Yin (Author), Jiang Zhong (Author)
• Format: Book
• Published: BMC, 2016-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Although current vaccination strategies have been successful at preventing a variety of human diseases, attempts at vaccinating against some pathogens such as AIDS and tuberculosis (TB) have been more problematic, largely because abnormally high numbers of antigen-specific CD8 + T cells are...