Triptolide Induces Leydig Cell Apoptosis by Disrupting Mitochondrial Dynamics in Rats

• Main Authors: Linyan Lv (Author), Yajie Chang (Author), Yanqing Li (Author), Haicheng Chen (Author), Jiahui Yao (Author), Yun Xie (Author), Xiaoyan Liang (Author), Xing Yang (Author), Min Zhang (Author), Guihua Liu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Triptolide is widely used in the clinical treatment of various diseases. Side effects, including reproductive toxicity to male patients, limit its application. However, no detailed mechanisms or potential intervention targets have been reported. In this study, we show that triptolide activated the m...