Truncated NPY-based NPY(Y1)R-specific radiopeptides: Improved in vivo PET tumor imaging by application of peptidase inhibitors

• Main Authors: Benedikt Judmann (Author), Nils F. Baier (Author), Henning Rudolf (Author), Güllü Davarci (Author), Björn Wängler (Author), Ralf Schirrmacher (Author), Gert Fricker (Author), Carmen Wängler (Author)
• Format: Book
• Published: Elsevier, 2024-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The neuropeptide Y receptor subtype 1 (NPY(Y1)R) exhibits high expression rates on human breast cancer and is therefore an important target structure for the sensitive and specific visualization and characterization of the disease by Positron Emission Tomography (PET). However, imaging of this recep...