Role of Estrogen Receptors α and β in a Murine Model of Asthma: Exacerbated Airway Hyperresponsiveness and Remodeling in ERβ Knockout Mice

• Autors principals: Rama Satyanarayana Raju Kalidhindi (Autor), Nilesh Sudhakar Ambhore (Autor), Sangeeta Bhallamudi (Autor), Jagadish Loganathan (Autor), Venkatachalem Sathish (Autor)
• Format: Llibre
• Publicat: Frontiers Media S.A., 2020-02-01T00:00:00Z.
• Matèries: article
• Accés en línia: Connect to this object online.

Epidemiological data suggests increased prevalence of asthma in females than males, suggesting a plausible role for sex-steroids, especially estrogen in the lungs. Estrogen primarily acts through estrogen-receptors (ERα and ERβ), which play a differential role in asthma. Our previous studies demonst...